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Damiana Leaf Extract and L-Arginine for Men: Two 10 mg Rows Against the Studies

Quick answer

Damiana leaf extract is a 5:1 extract of a shrub's leaf, and HoneyBoost lists 10 mg per gummy, about 50 mg of leaf (10 x 5). L-arginine is an amino acid, also 10 mg. We found no human trial of damiana alone. Arginine trials used 1,500 to 5,000 mg a day, so the gummy holds under 1% of that.

Written by the HoneyBoost label deskUpdated · 5 min read

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What does research say about damiana leaf extract?

Little in people: a review found that damiana's aphrodisiac reputation rests on chemical, cell and animal work, with human data only in herb blends (Szewczyk 2014, damiana).

The HoneyBoost panel lists "Damiana (Turnera diffusa) Leaf Extract 5:1", 10 mg per gummy (HoneyBoost label). At 5:1 that stands for about 50 mg of leaf (10 x 5). Because no human trial of damiana alone turned up, we have no studied dose to set it against. We read no damiana safety source, so ask a pharmacist about medicines.

What do studies say about L-arginine for men?

They are mixed, and they used far more than 10 mg.

A pooled review covered 10 trials in 540 men with mild to moderate erectile dysfunction, at 1,500 to 5,000 mg a day (Rhim 2019, arginine ED). A Mayo Clinic page says oral arginine "might improve sexual function in men with ED due to a physical cause" and notes it can lower blood pressure (Mayo Clinic, L-arginine). Another summary calls the evidence mixed (MSK, Arginine).

The gummy's 10 mg is under 1% of 1,500 mg (10/1,500). No trial tested HoneyBoost, so none of this carries over.

How far below the studied amounts are the 10 mg rows?

Far below wherever a studied amount exists, and for damiana there is nothing to compare.

  • Maca (root equivalent)100 mg on the label

    Studies: gelatinized maca 1,500 and 3,000 mg a day (12 weeks) and a maca extract at 2,400 mg a day; the label's 10 mg extract equals 100 mg of root (10 x 10). Studies used about 15 to 30 times the label amount. (Gonzales 2002, maca desire and T) (Zenico 2009, maca and mild ED)

  • Horny goat weed80 mg on the label

    No human trial of horny goat weed extract at this dose was found; the reviews describe mostly cell and animal work. No human trial range found. (Niu 2022, icariin review) (Meng 2026, icariin and ED)

  • Damiana (leaf equivalent)50 mg on the label

    No human trial of damiana alone was found; human data come only from herb blends. No human trial range found. (Szewczyk 2014, damiana)

  • Tongkat ali (extract)25 mg on the label

    Studies: 200 mg a day of extract for one to three months in two open-label studies; the label's row is 25 mg of extract (equal to 2,500 mg root). Studies used about 8 times the label amount. (Tambi 2012, tongkat ali LOH) (Tambi 2010, tongkat ali fertility)

  • Mucuna (seed extract)10 mg on the label

    Study: 5 g (5,000 mg) of seed powder a day for three months, uncontrolled; the label's row is 10 mg of an extract at 98% L-DOPA. Studies used about 500 times the label amount. (Shukla 2010, mucuna in men) (RIVM 2024, mucuna risk assessment)

  • L-arginine10 mg on the label

    Studies: 1,500 to 5,000 mg a day in men with mild to moderate ED (10 trials) and 6 g a day in one trial. Studies used about 150 to 500 times the label amount. (Rhim 2019, arginine ED) (Menafra 2022, arginine ED)

  • Zinc (as gluconate)2.5 mg on the label

    Reference levels: 11 mg a day recommended for men and 40 mg a day upper limit for adults (NIH); not study doses. A reference level, not a study dose: the label is 6% of the higher level. (NIH ODS, zinc) (Prasad 1996, zinc and T)

Log scale: each gridline is ten times the one before. Studied ranges are daily amounts from the trials linked on each row; rows marked as a reference show a reference level, not a study dose. A bar being far away does not mean the gummy is unsafe or useless; it means the study results cannot be borrowed for it, because none tested HoneyBoost or this combination.

Label rows against studied amounts
RowLabelStudied
Damiana leaf extract 5:110 mg (about 50 mg leaf)No human trial alone
L-arginine10 mg1,500 to 5,000 mg a day

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Who should check with a clinician about arginine?

Anyone with heart disease, a past heart attack or blood pressure medicine should check first.

In 153 patients after a heart attack, arginine brought no benefit and more deaths, and the authors said it should not be recommended after one (Schulman 2006, VINTAGE MI). Erectile problems can come with heart disease, so see a clinician. Read medicine interactions.

Keep taking prescribed medicine; chest pain, fainting or trouble breathing: 911; an erection lasting 4 hours or more: emergency room. The wrap prints no suggested-use line.

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FAQ

HoneyBoost questions people ask

Does damiana have human studies?

Not alone, as far as we found. The review we read says human data exist only for herb blends. No trial tested HoneyBoost.

How much L-arginine is in HoneyBoost?

The panel prints 10 mg per gummy. Studies in men with erectile dysfunction used 1,500 to 5,000 mg a day, so the gummy holds under 1% of the lowest studied amount (10/1,500).

Can arginine affect blood pressure?

Yes. Mayo Clinic notes oral arginine can lower blood pressure; 11 trials pooled found a 5.4 mm Hg drop in systolic pressure at 4 to 24 g a day. Ask a pharmacist if you take blood pressure medicine.

Who wrote this

Written and reviewed by

Written byThe HoneyBoost label deskHoneyboostmen, U.S. stocking partner for HoneyBoost

Pages built from the label, the seller's brief and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Casey McCraw, MD, PhysicianRole: Medical reviewerReview date: October 31, 2026

Last updated . Read our editorial standards and how we check reviews. This website is the information site of a U.S. stocking partner for HoneyBoost. It is not the manufacturer, and the label names GEX Corp LLP (Florence, Kentucky) as the distributor. We earn money when you buy through our order links.

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